Under this circumstance, try running Fallout 4 in compatibility mode to fix the crashing error. Fallout 4 crash on launch: It indicates that Fallout 4 stops working when launching this game on Windows 10.
It is terrible as it may damage your computer. Generally, Fallout 4 crashing error can be divided into 4 cases ( Fallout 4 keeps crashing, Fallout 4 crashing PC, Fallout 4 crash on launch, and Fallout 4 crash on Xbox One).